TB-500 5MG

TB-500 (Thymosin Beta-4) is a synthetic version of a naturally occurring thymosin β4 peptide, which has been widely studied for its potential role in cellular regeneration, wound healing, and angiogenesis. Researchers have explored TB-500’s effects on tissue repair, inflammation modulation, and neuroprotective mechanisms in preclinical studies.

TB-500 & Nasal Administration in Research

Recent research has investigated the feasibility of intranasal TB-500 delivery as a non-invasive method of administration. Potential research advantages of nasal spray application include:

• Bypassing first-pass metabolism, leading to higher systemic absorption
• Potential neuroprotective effects via the olfactory and trigeminal pathways
• Rapid uptake and circulation, potentially allowing for efficient systemic research applications

While subcutaneous and intravenous routes are traditionally studied, nasal delivery is emerging as a potential research method for systemic and neurological pathways.

Mechanism of Action & Research Applications

TB-500 has been researched for its ability to modulate actin, a key protein involved in cell migration, tissue growth, and wound repair. Preclinical studies suggest it may play a role in:

✔ Wound Healing & Tissue Regeneration – Studies indicate it may stimulate angiogenesis (blood vessel growth) and cell migration.
✔ Muscle & Tendon Recovery – Research suggests it may assist in reducing fibrosis and promoting tissue remodeling.
✔ Neuroprotective Effects – Some studies explore its influence on cognitive function, nerve repair, and neuroinflammation.
✔ Anti-Inflammatory Potential – Preclinical models suggest it may help modulate cytokine activity and oxidative stress.
✔ Cardiovascular Research – Studies suggest it may play a role in cardiac tissue repair and vascular function.

Molecular & Structural Information

• Molecular Formula: C212H350N56O78S
• Molecular Weight: 4963.5 g/mol
• Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Ala-Glu-Asp-Gly-Gln-Ser-Gly-Glu-Gly-Glu-Thr-Gln-Glu-Lys-Glu-Ser

Storage & Stability

• Store at -20°C for long-term stability
• Keep in a light-protected, cool environment
• Reconstitute with research-grade solvents

Legal & Research Disclaimer

TB-500 is for research purposes only. It is not for human consumption, medical use, or diagnostic applications. All information is provided for scientific and educational research.