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SLU-PP-332 1G
$50.00
Bulk pricing available for quantities of 3 units or more
In stock: 15 available
Buy more, save more
| Quantity | Price per item | Discount |
| 3 items | $47.50 | 5% off |
| 5 items | $45.00 | 10% off |
Product Details
SLU-PP-332 (Research Compound)
1 GRAM RAW POWDER
For Research Purposes Only — Not for Human or Veterinary Use
SLU-PP-332 is a synthetic small-molecule compound that functions as a potent agonist of the estrogen-related receptors (ERRα/β/γ). These nuclear receptors are central regulators of energy metabolism, mitochondrial biogenesis, and aerobic capacity. By selectively activating these pathways, SLU-PP-332 provides researchers with a unique tool for exploring the cellular and molecular mechanisms that underlie energy expenditure, exercise adaptation, and metabolic health.
Scientific Background
Mechanism of Action: SLU-PP-332 binds to ERRs and modulates transcriptional programs linked to mitochondrial activity and oxidative metabolism.
Potency: Reported half-maximal effective concentrations (EC₅₀) are approximately 98 nM for ERRα, 230 nM for ERRβ, and 430 nM for ERRγ, based on cell-based assay data.
Classification: Non-peptidic, small-molecule ERR agonist.
Reported Preclinical Findings
In published animal and cellular studies, SLU-PP-332 has been observed to:
Enhance mitochondrial respiration and fatty acid oxidation.
Promote a shift toward oxidative muscle fibers and endurance-related phenotypes.
Improve whole-body energy expenditure, insulin sensitivity, and metabolic flexibility in rodent models of obesity.
Extend running capacity and endurance in experimental models.
These results make SLU-PP-332 a valuable research probe for investigating exercise-mimetic mechanisms, mitochondrial function, and potential metabolic disease pathways.
Applications in Research
Metabolism & Obesity Research — Study energy balance, lipid utilization, and insulin sensitivity.
Mitochondrial Biology — Explore bioenergetic regulation and oxidative phosphorylation.
Exercise Physiology — Model the molecular adaptations to endurance training.
Drug Discovery Tool — Validate ERR-targeted pathways in preclinical models.
Important Notice
SLU-PP-332 is provided strictly for laboratory research use only. It is not approved for diagnostic, therapeutic, or clinical applications in humans or animals. No dosing, administration, or medical guidance is provided or implied. Proper laboratory safety practices, including use of personal protective equipment (PPE) and institutional biosafety oversight, are required when handling this compound.
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SLU-PP-332 1G
