PT-141 10MG X 10ML NASAL SPRAY

PT-141 (Bremelanotide) – 10mg Vial

For Research Use Only In 20ML Nasal Sprayer

PT-141 is a synthetic melanocortin receptor agonist derived from Melanotan II. It has been studied for its effects on melanocortin receptors (MC1R–MC5R), particularly in arousal, vasodilation, and neurological research. Unlike PDE5 inhibitors, PT-141 may act centrally through dopaminergic pathways, making it a unique subject of CNS-based studies.

Research Focus Areas

Arousal & Motivation Studies – Activation of MC3R/MC4R in the hypothalamus

Neurological & Dopaminergic Pathways – Mood, reward, and CNS signaling

Vasodilation & Circulatory Models – Investigating non-NO pathway mechanisms

Melanocortin Receptor Function – Hormonal and neuroendocrine studies

Nasal Administration in Research

Intranasal delivery is commonly studied for its ability to bypass first-pass metabolism and enhance brain penetration via olfactory and trigeminal pathways.

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Molecular Data

Formula: C50H68N14O10

Weight: 1025.2 g/mol

Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-O

Storage Guidelines

Store at -20°C

Keep in a cool, dark environment

Reconstitute with sterile water or research-grade solvents

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Disclaimer: For laboratory research only. Not for human or veterinary use.