INC-R8 60 CAPSULES

INC-R8 | Multi-Compound Research Formulation

INC-R8 is a three-component research formulation containing GW-501516, BAM-15, and SLU-PP-332. The constituent compounds have been investigated independently in experimental models involving nuclear-receptor signaling, mitochondrial bioenergetics, cellular respiration, and regulation of oxidative metabolism.

The formulation is supplied as a standardized research material for laboratory and analytical applications. It is not intended to represent an approved therapeutic combination, and the combined formulation has not been established as safe or effective for human use.

Research Components

GW-501516

GW-501516 is a synthetic small-molecule agonist of peroxisome proliferator-activated receptor delta (PPARδ). It is used experimentally to investigate PPARδ-mediated transcription and pathways associated with lipid metabolism, substrate utilization, and cellular energy regulation. Commercial biochemical suppliers characterize GW-501516 as a potent and selective PPARδ agonist. 

BAM-15

BAM-15 is an experimental mitochondrial protonophore/uncoupler. Preclinical research has examined its effects on mitochondrial membrane potential, proton conductance, oxygen consumption, oxidative phosphorylation efficiency, and cellular bioenergetics. Uncoupling mitochondrial respiration can substantially alter cellular energy balance, making experimental conditions and appropriate controls particularly important. 

SLU-PP-332

SLU-PP-332 is an experimental small molecule investigated as an agonist of estrogen-related receptors (ERRs). Preclinical research has examined ERR-mediated transcriptional programs associated with oxidative metabolism, mitochondrial function, and cellular energetic adaptation. Available evidence remains predominantly preclinical and should not be interpreted as establishing clinical effects or human safety. 

Composition

Per capsule:

GW-501516 — 7.5 mg

BAM-15 — 5 mg

SLU-PP-332 — 2.5 mg

Quantity: 60 capsules

Research Context

The three constituents interact with distinct experimental targets rather than representing three versions of the same mechanism. GW-501516 is principally associated with PPARδ signaling; BAM-15 with mitochondrial proton conductance and oxidative phosphorylation; and SLU-PP-332 with ERR signaling. This makes the individual compounds relevant to different areas of cellular-energy and metabolic research. 

Importantly, findings reported for an individual constituent cannot automatically be extrapolated to this combination. Combination-specific pharmacology, interactions, safety, and biological effects have not been established merely because the individual compounds have been studied separately.

Research-Use Statement

FOR RESEARCH PURPOSES ONLY. NOT FOR HUMAN OR VETERINARY USE.

INC-R8 is offered exclusively as a research material. It is not a dietary supplement, food, drug, cosmetic, or therapeutic product and is not intended for ingestion, administration, diagnosis, treatment, mitigation, cure, or prevention of disease.