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Follicle Fuel — Research Compound
30 mL | For Laboratory Research Use Only
Active Components:
Minoxidil 5%
Finasteride 0.1%
Caffeine 1%
Niacinamide 1%
Ghkcu 1%
Research Overview
Follicle Fuel is a topical research formulation designed for investigational studies related to hair follicle biology, scalp physiology, and androgen-related follicular signaling pathways. This compound combines well-characterized actives that have been independently studied in dermatological and trichological research models.
Ingredient Research Context
Minoxidil (5%)
Minoxidil is a potassium channel opener extensively studied for its effects on hair follicle cycling. Published research indicates it may:
Prolong the anagen (growth) phase of the hair cycle
Increase follicular size and shaft diameter
Enhance local scalp blood flow
The 5% concentration has been widely evaluated in clinical and investigational settings and is associated with greater efficacy signals compared to lower concentrations in hair density and regrowth endpoints.
Finasteride (0.1%)
Finasteride is a type II 5-alpha-reductase inhibitor that reduces conversion of testosterone to dihydrotestosterone (DHT). Research into topical finasteride focuses on:
Localized reduction of scalp DHT
Mitigation of follicular miniaturization
Potential minimization of systemic exposure relative to oral administration
Topical concentrations in the 0.1%–0.25% range are commonly explored in experimental studies.
Caffeine (1%)
Caffeine has been examined in in-vitro and ex-vivo hair follicle models for its potential to:
Stimulate dermal papilla cell activity
Counteract testosterone-induced growth suppression
Support follicular energy metabolism
Its role in combination formulations remains an area of ongoing investigation.
Niacinamide (1%)
Niacinamide (vitamin B3) is studied for its effects on skin and scalp health, including:
Support of barrier function
Modulation of inflammatory signaling
Enhancement of local microenvironment conditions surrounding follicles
While not a primary hair growth agent, it is frequently included in research formulations to support scalp integrity.
Research Considerations
Multi-mechanism approach: Targets vascular activity, androgen signaling, follicular stimulation, and scalp condition
Evaluation endpoints: Hair count, shaft thickness, anagen/telogen ratios, scalp DHT levels, and tolerability markers
Use context: Intended for laboratory, analytical, or educational research only
Important Notice
For research use only. Not for human or veterinary use.
This product is not intended to diagnose, treat, cure, or prevent any disease.
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